We found that when gentamycin was used in those who were suffering from respiratory failure, the pharmacokinetic parameters presented marked changes, an extention of the half-life period and a slowing down of the rate of elimination of the drug. 发现有呼吸衰竭者,应用此药时,其药动参数有明显改变,表现为半衰期延长,消除速率减慢。
The half-life of MTX-ms in vivo was 2.14 times as much as that of MTX solution. During the assay period of sixteen hours the drug concentration of MTX-ms in hepatic vein blood was constantly higher than that of MTX solution. 微球药物消除半衰期为MTX溶液的2.14倍,在16h的体内检测中,肝静脉局部的MTX-ms血药浓度始终高于MTX溶液组。
Conclusion: The method of doubling dosage within the first half-life period can obviously improve the dependence in patients with rheumatoid arthritis. 结论:第一个半衰期剂量加倍法可明显提高类风湿关节炎病人的依从性。
THE THEORETICAL PREDICTION OF CYCLING DURABILITY FOR THE HYDROGEN-STORAGE ELECTRODE(ⅰ) Application of Half-Life Period Method With Constant Voltage Terminal Point Discharging 贮氢材料电极循环寿命的定量预测(Ⅰ)&定终点电位放电半衰期法的应用
The remove of chlorothalonil and triazolone in grape followed the first-order dynamics, the half-life period of are 2.68 and 2.83 days at room temperature. 百菌清和三唑酮在葡萄中的自然去除遵循一级动力学方程,室温下的半衰期分别为2.68天和2.83天。
[ Objective] Exogenous growth factors have a short half-life period, which are diluted and metabolized in vivo. 目的:外源性成骨生长因子半衰期短,在体内使用很快被稀释和代谢。
Since the natural enzyme has a short half-life period and a poor stability. 天然酶的半衰期短,稳定性差。
While it is generally considered that pyrethroid pesticides have the characteristics of high efficiency and low toxicity, but they also have optical and thermal stability characteristics, therefore, they have long half-life period in environment, and very difficult to degrade rapidly under natural conditions. 虽然人们普遍认为拟除虫菊酯类农药具有高效低毒的特性,但是它同时具有对光、热稳定的特点,所以,在环境中半衰期较长,很难在自然条件下快速降解。
IGFBPs in circulation system of the animal organisms can bind the IGFs, regulate IGFs half-life period and enhance IGFs biological activity. IGFBPs在体内循环系统中能与IGFs结合,调控IGFs的半衰期,提高IGFs的生理活性。